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Corante Blogs

Corante Blogs examine, through the eyes of leading observers, analysts, thinkers, and doers, critical themes and memes in technology, business, law, science, and culture.

The Press Will Be Outsourced Before Stopped

Vin Crosbie, on the challenges, financial and otherwise, that newspaper publishers are facing: "The real problem, Mr. Newspaperman, isn't that your content isn't online or isn't online with multimedia. It's your content. Specifically, it's what you report, which stories you publish, and how you publish them to people, who, by the way, have very different individual interests. The problem is the content you're giving them, stupid; not the platform its on."
by Vin Crosbie in Rebuilding Media

Travels In Numerica Deserta

There's a problem in the drug industry that people have recognized for some years, but we're not that much closer to dealing with it than we were then. We keep coming up with these technologies and techniques which seem as if they might be able to help us with some of our nastiest problems - I'm talking about genomics in all its guises, and metabolic profiling, and naturally the various high-throughput screening platforms, and others. But whether these are helping or not (and opinions sure do vary), one thing that they all have in common is that they generate enormous heaps of data.
by Derek Lowe in In the Pipeline

Disrobing the Emperor: The online “user experience” isn't much of one

Now that the Web labor market is saturated and Web design a static profession, it's not surprising that 'user experience' designers and researchers who've spent their careers online are looking for new worlds to conquer. Some are returning to the “old media” as directors and producers. More are now doing offline consulting (service experience design, social policy design, exhibition design, and so on) under the 'user experience' aegis. They argue that the lessons they've learned on the Web can be applied to phenomena in the physical and social worlds. But there are enormous differences...
by Bob Jacobson in Total Experience

Second Life: What are the real numbers?

Clay Shirky, in deconstructing Second Life hype: "Second Life is heading towards two million users. Except it isn’t, really... I suspect Second Life is largely a 'Try Me' virus, where reports of a strange and wonderful new thing draw the masses to log in and try it, but whose ability to retain anything but a fraction of those users is limited. The pattern of a Try Me virus is a rapid spread of first time users, most of whom drop out quickly, with most of the dropouts becoming immune to later use."
by Clay Shirky in Many-to-Many

The democratisation of everything

Over the last few years we've seen old barriers to creativity coming down, one after the other. New technologies and services makes it trivial to publish text, whether by blog or by print-on-demand. Digital photography has democratised a previously expensive hobby. And we're seeing the barriers to movie-making crumble, with affordable high-quality cameras and video hosting provided by YouTube or Google Video and their ilk... Music making has long been easy for anyone to engage in, but technology has made high-quality recording possible without specialised equipment, and the internet has revolutionised distribution, drastically disintermediating the music industry... What's left? Software maybe? Or maybe not."
by Suw Charman in Strange Attractor

RNA Interference: Film at Eleven

Derek Lowe on the news that the Nobel Prize for medicine has gone to Craig Mello and Andrew Fire for their breakthrough work: "RNA interference is probably going to have a long climb before it starts curing many diseases, because many of those problems are even tougher than usual in its case. That doesn't take away from the discovery, though, any more than the complications of off-target effects take away from it when you talk about RNAi's research uses in cell culture. The fact that RNA interference is trickier than it first looked, in vivo or in vitro, is only to be expected. What breakthrough isn't?"
by Derek Lowe in In the Pipeline

PVP and the Honorable Enemy

Andrew Phelps: "Recently my WoW guild has been having a bit of a debate on the merits of Player-vs.-Player (PvP) within Azeroth. My personal opinion on this is that PvP has its merits, and can be incredible fun, but the system within WoW is horridly, horribly broken. It takes into account the concept of the battle, but battle without consequence, without emotive context, and most importantly, without honor..."

From later in the piece: "When I talk about this with people (thus far anyway) I typically get one of two responses, either 'yeah, right on!' or 'hey, it’s war, and war isn’t honorable – grow the hell up'. There is a lot to be said for that argument – but the problem is that war in the real historical world has very different constraints that are utterly absent from fantasized worlds..."
by Andrew Phelps in Got Game

Rats Rule, Right?

Derek Lowe: "So, you're developing a drug candidate. You've settled on what looks like a good compound - it has the activity you want in your mouse model of the disease, it's not too hard to make, and it's not toxic. Everything looks fine. Except. . .one slight problem. Although the compound has good blood levels in the mouse and in the dog, in rats it's terrible. For some reason, it just doesn't get up there. Probably some foul metabolic pathway peculiar to rats (whose innards are adapted, after all, for dealing with every kind of garbage that comes along). So, is this a problem?.."
by Derek Lowe in In the Pipeline

Really BAD customer experience at Albertsons Market

Bob Jacobson, on shopping at his local Albertsons supermarket where he had "one of the worst customer experiences" of his life: "Say what you will about the Safeway chain or the Birkenstock billionaires who charge through the roof for Whole Foods' organic fare, they know how to create shopping environments that create a more pleasurable experience, at its best (as at Whole Foods) quite enjoyable. Even the warehouses like Costco and its smaller counterpart, Smart & Final, do just fine: they have no pretentions, but neither do they dump virtual garbage on the consumer merely to create another trivial revenue stream, all for the sake of promotions in the marketing department..."
by Strange Attractor in Total Experience

The Guardian's "Comment is Free"

Kevin Anderson: "First off, I want to say that I really admire the ambition of the Guardian Unlimited’s Comment is Free. It is one of the boldest statements made by any media company that participation needs to be central to a radical revamp of traditional content strategies... It is, therfore, not hugely surprising to find that Comment is Free is having a few teething troubles..."
by Kevin Anderson in strange

The Loom

Date Index
June 2006
09: Host Shifting

May 2006
31: Small Girls with Sharp Rocks
29: Adapting to Life in Yogurt
25: Talking at Woods Hole
23: Invisible Gladiators in the Petri Dish Coliseum
23: Synthetic Biology--You are There
22: Manimals, Sticklebacks, and Finches
18: Jakob the Hobbit?
17: Grandma Manimal
16: Hominids for Clinical Trials--The Paper
16: The Neanderthal Genome Project Begins
15: Unauthorized Wiretaps in the Garden
11: In the Beginning Were the Viruses
10: Gamma Ray Bursts--One Less Thing to Worry About
08: Talking Tiktaalik
05: Crayfish Psychoanalysis
03: Worst Science Article Headline Ever?
02: Wanted: Hominids for Clinical Drug Trials
02: Speak, Starling
01: Snakes, Universes, and the Rest

April 2006
11: Brains and Bones and Radios
10: The Great Escape
10: The Final Adventures of the Blind Locksmith
07: The Blind Locksmith Continued: The Mushy Definition of Complexity
06: The Blind Locksmith
06: Leech quest
06: Back to Blogging
05: Walking Towards Land

March 2006
31: Learning To Ignore Your Viruses
28: Not Dead, Just Deadlines
23: You're a Dim Bulb (And I mean that in the best possible way)
22: Kate Wong on the Hobbit Trail
19: Pharyngula on penguins
17: Gross, and then really gross
17: Hipster Dodos
14: Evolution Resumes in November!
14: Frivolous Creationist Lawsuits
13: Mothers, Children, and Genes in Conflict
13: The Sixty-Million-Year Virus
11: A Retraction and a Deletion
10: Taking the Temperature on Global Warming Books
10: Lemonick Blogs
10: Caution: Contains Viewing Material That May Not Be Suitable for Younger Cockroaches
10: Cockroach Zombies Go Cable
09: Where There's Liquid Water...
09: Wrist Walkers Revisited
08: This Week in Human Evolution
03: Tree of Life, c. 2006

February 2006
27: Set Your Watch
22: The Dawn of Brains and Bones
21: Painting Evolution
20: The Origin of Species, Side By Side
20: The Evolution of 3-D
17: Randy "Flock of Dodos" Olson Speaks
16: Nice Company
14: Answers to your parasite questions
14: Movie Night
11: DailyKos Interview
10: What to do after you lose your job at NASA
09: Kid, Someday Your Name Will Be in Lights
08: Do Not Arm-Wrestle With Hobbits
08: A Flock of Dodos, trailed by a journalist
08: Irish elk of the Jurassic
07: Hey Wonkette!
06: Leechfest 2006: "We are Always the Bait"
02: The Wisdom of Parasites

January 2006
26: Crocodiles and Sentence Diagrams
26: Plagiarizing Dinosaurs
25: Darwiniana
17: The Return of the Puppet Masters
17: Comment Jam
12: Science Blog Convergence
11: A Complicated Death
10: They Just Keep Piling On
06: Updated Cat Evolution
06: And Introducing Our Latest Creationism-Friendly Politician, The Governor of Texas!
05: Cat-Blogging from Deep Time
03: Let Me Draw Your Attention...
03: On the Virtual Radio Tomorrow
02: In Praise of Flukes
01: Michigan Talk

December 2005
30: Stumbling On Through the Blogosphere
28: More Fun With Our Post-Modern Politicians
26: The Other Panda's Thumb
21: Semiotics of a Leaf--The Dope
21: The Big Fact-Check: Thoughts On the Day After Dover
20: Tree or Trellis--The Dope
20: Dover: ID is out!
15: Conservative leader: Intelligent Design is "bull----"
12: Chimpanzees at Pre-School
06: Tree or Trellis
01: Quote Mining, Near and Far
01: Updating Human Evolution

November 2005
29: An Audubon for the Miocene
28: Six-Legged History
28: Half a Mil
28: The Mosquito and the Bottle
21: Which Came First, the Snake or the Venom?
18: Book News, Part Two
17: Book News, Part One
14: Chronicle of a Death Foretold
07: The Long, Long Sleep
05: Beware of Crickets Bearing Gifts
03: Stay Right There, Mendel

October 2005
30: The Semiotics of a Leaf
28: More from Brown on Hobbits
28: Be heard!
27: Monkey Business
27: Hobbit As Monkey?
26: A Rough Grunt Dictionary
25: Where Is Your I?
25: The Loom: The Podcast Edition
24: Attention Nutmeggers Again
24: Now That's A Petition
24: Blog Notes
17: My blog, your microphone
16: What's A Gene For?
15: Of zoos and polls
14: Whose Brain Is It Anyway? (The Further Hobbit Adventures)
11: Hobbits again
10: A 70-Million-Year March of the Penguins
10: Florida, Where The Living Is Contradictory
08: The Book Stack
05: Attention Nutmeggers
04: Evolution's Emily Litella?
03: Okay, It's Not A Nobel, But It's Still Nice
03: A Prize Bug

September 2005
29: The Bumpy Road to an Upgrade
25: Swarthmore Evolving
22: Blogs: Another Sign of Semi-Respectability
22: The Steps of the Puzzle
19: A Trip to the Museum
15: Part Human, Part Virus
14: Traditional Norms, Animal-style
13: Text Versus Subtext
12: Monday Morning Buffet

August 2005
31: Clint Is Dead, Long Live Clint
29: The Chromosome Shuffle
28: The Beauty of Deceit
24: Deepak Chopra Explains It All For You: Conscious Photons!
24: Bush, Frist...McCain
24: The Kanisza Virus
23: A View From the Left (Sigh)
23: Malaria For Brains
22: The Tubercular Hominid
21: The Big Picture
18: Updates
16: Ghosts in the E. coli machine
14: Meet Your Inner Mole Rat
11: A Dog and the Mind of Newton
08: Sickness All Around
05: And Now A Word From the Astronomers...
03: 55,000 Science Teachers: "Stunned and Disappointed" by the President
02: 43,000 Scientists: Bush Puts Schoolchildren At Risk
02: A Question For The President
01: Singing Wings, Or Natural Selection's Lesser Known Sibling

July 2005
12: An iPod in Your Head
08: Tangling the Tree
05: Return of Mad Cow Memories
01: It Never Hurts to Ask

June 2005
30: Mice, Monkeys, and Muttering
28: Lucky Octopi
23: Evidence and exasperation
21: Light from Dark
21: Surprises in Jelly
16: Look! Up in the Sky! Flying Hobbits!
15: Return to Hobbit Limbo
09: O is for...
05: An Inordinate Fondness for Beetle Horns

May 2005
19: Of Stem Cells and Neanderthals: Closing the Circle
10: Brain Revolutions, Old and New
04: The Mutiny Down Below
02: Cheating on the Brain
01: Woodpecker Punditry--Predicted and Delivered!

April 2005
30: What the Loom Giveth, the Google Ads Taketh Away
29: Hobbits Alive?
28: Reports of My Extinction Are Greatly Exaggerated
25: Life Versus Squiggles
13: Humanity's Map
12: "Blinding New Evidence!"
12: Trouble in Middle Earth?
11: Zap
06: Flesh on the Bone
04: Doctor Venom

March 2005
30: Love Darts in the Backyard
28: Dinosaurs Hit the Airwaves
23: Move Over, Mendel (But Don't Move Too Far)
21: Who Gets On the Shelf?
21: Tree Climbing
18: Evolution at Work (and creationism nowhere in sight)
16: Growing Up With Dinosaurs
07: Darwin in the Crib
03: The Hobbit's Brain
01: Conscientious Chimps and Bold Birds
01: Building Gab: Part Two

February 2005
25: Building Gab: Part One
24: Return of the Prodigal Bones
16: Eyes, Part Two: Fleas, Fish, and the Careful Art of Deconstruction
15: Eyes, Part One: Opening Up the Russian Doll
15: This Week's Table of Contents: Eyes and Language
12: Metaphor, Me-ta-phor!
08: Consciousness and the Culture Wars, Part Three
08: Gulp
04: Farewell, Ernst

January 2005
28: Mutants Today and In Days Gone By
27: The Incredible Shrinking Fish and Other Wonders of the Modern World
23: Of Stem Cells and Neanderthals
21: Non-Random Sponsor
18: The Hobbit War: An Indonesian View
14: Like the Elections, Except in Outer Space
13: Scrape off Those Stickers!
13: More To Read: Tangled Bank
12: Dinosaur-eating Mammals (You heard me right)
10: Mysteries Near and Far
08: Aliens Invade East Lansing
06: From Enemies to Friends

December 2004
31: The Whale and the Antibody
29: Ms. Schlafly, You Receive an F
27: All the News That's Too Big To Print
16: When It Pays To Be Dumb
13: Taking Crichton Down a Peg
10: Climate: A Promising Blog
10: Idealogy Versus Isotopes
10: Hominid Sculpture
09: Bones on the Loose
06: Resurrecting Genomes
03: Hobbit Update

November 2004
30: Getting Sexier All The Time
26: Canada Evolving
26: Hobbit Limbo?
22: Technology for Nature
19: Old Apes and Bad Links
19: Can Two-Thirds of Americans Possibly Be Wrong?
18: An Award (And An Apology)
10: Best of 2004
03: What is Old is New
03: The Morula Solution?

October 2004
29: Intelligent Redesign
26: Island of the Lost Hominids
25: Hacking Life
21: The God Gene Meme
18: In The Papers
17: Genetic Ghosts of Hominids Past
16: The Missing Foe
16: The Ancestor's Tale Reviewed
15: Further Adventures in Geological Cowardice
13: Ignorance For Sale, Thanks To Your Tax Dollars
11: More on Common Ancestors
11: Biting the Dust
04: If These Lice Could Talk
04: Nobel and Darwin

September 2004
23: A Puzzle for the Autumnal Equinox
20: The Long Road from Genes to God
15: Babies with Grown-up Brains
13: Deep Time In a Bird's Beak
02: A Blog-Free Week
02: Getting Closer To Life's Dawn
01: The Unwritten Self

August 2004
30: Channel Surfing For The Inner Chimp
27: Takes One to Know One
26: Deadly, Tiny, and Ready For Its Close-up, Mr. DeMille
25: Spite in a Petri Dish
23: Adam and His Eves
22: Blog Revived

July 2004
08: Mooney on the Science War
07: Evolution meets IVF
05: Dawn of the Leafy Age
02: The Little Ones

June 2004
30: Machiavellian Monkeys
21: Taking the Plunge
16: Love Is A Virus
15: The Inescapable Allure of the Reptile Brain
03: No Press Releases, Please
03: Battle of the Hole Punchers
01: From Souls to Genes
01: Mister Adaptation
01: All in the Australian Mind
01: The Wi-Fi Within

May 2004
18: Ugly Comments, Quiet Blogger
04: New Life For Old
03: Very Noisy Evolution

April 2004
22: In the Beginning Was the Borehole
21: Right and Wrong and Radio
21: The Game is Over
21: Back
04: Oh To Be In England

March 2004
29: Light Blogging
24: The Panda's Thumb
24: Chew On This
24: Getting Closer to the Brain Implant
23: Soul of the South
22: The Reviews
22: The Dog That Didn't Bark In the Night
18: Angels and Extinctions
17: Fire Up The Tivo
17: Literature Check
15: The Accidental Tumor
12: The Wisdom of the Mailbox
10: Ohio Loses Its Way
09: Bioethics of--and in--the Brain
09: Building and Breaking The Mental Juke-Box
05: The Loom In the News
05: Secrets of the Teeth
02: The Dawn of Medicine, Plus or Minus a Couple Million Years
02: 17th Century Soul, 21st Century Mind
02: The Creativity of Microbes

February 2004
29: Networks Under Construction
26: Return of the Howlers
18: West Coast Soul, or How to Get on TV
12: My Darwinian Daughters
09: Flesh Air
06: Flower Power
05: Aristotle, Darwin, Watson, and Co. Now Online
05: The Monkeys Win
05: Where Have I Heard "Sound Science" Before...?
05: Unsound unscience

January 2004
30: No SARS in Georgia
26: Midtown and Downtown
26: Beyond the Cycle
23: Advances in Deception
23: You Know What They Say About Male Beetles With Long Horns...
20: Today's Lunch Special
20: The Howler Test
14: Orchid Hacks
14: A Notice to Subscribers
12: Never Mind That Boiling Kettle...
12: Of Radio Shows and Pirate Neurologists
11: Month One/Staying in Touch
09: Building the World from the Brain Out
07: Talking Soul In DC
07: The Loom's Celebrity Edition
04: Big Science and Big Science Books
02: Brains, Past and Future

December 2003
31: William Safire's 2004 Predictions
30: Why The Cousins Are Gone
24: Mad Cow Memories
22: Your Loss is Your Gain
18: A Little Soul For The Holidays
18: Hamilton's Fall
17: The Genes Behind Big Brains
15: Reading the Body
12: A (Re) Introduction, Complete With Rams, Plagues, and Chimps
03: Eight Little Piggies Redux
03: Venter's Virus--Assembly Instructions Now On-Line
01: Free Will Starts...Now

November 2003
26: The Junk DNA Preservation Society
24: On the radio
23: Pinker's Choice
21: The History of An Orange Glow
19: Bad Memes in Oslo
18: This is your brain on racism. Or is that liberal guilt?
13: Suffering and Knowing
13: Microbe or Mineral?
13: Venter's virus
12: Recoil from Dollo's Law
11: The Hypothetical Fungus
07: Giving skepticism a bad name
07: More fun with Gregg
04: Junkburst
02: Chimps in the land of cheese

October 2003
31: Gross to you, gross to me
30: Reading on the Radar
29: Smart Wings of the Jurassic
28: Multi-Dimensional Mangling
26: Stalking the Perfect Tree
23: Consciousness and the culture wars, part 2
21: One gene, many fish
17: From Genes to Words
17: Soul Made Flesh: A Preview
15: 10% Myth, 1% Fact?
13: Rime of the Ancient Parasite
10: Heartache is brainache
09: A Picture of Not Thinking
07: The New Pangaea
07: Consciousness and the Culture Wars
06: Dreams of a Eugenicist Planet?
05: A New Species of Genius
05: Fear of a Eugenicist Planet
02: Divine Worms

September 2003
28: You Call That Fair?
27: The Reverse Broca
26: Blog birth