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Corante Blogs

Corante Blogs examine, through the eyes of leading observers, analysts, thinkers, and doers, critical themes and memes in technology, business, law, science, and culture.

The Press Will Be Outsourced Before Stopped

Vin Crosbie, on the challenges, financial and otherwise, that newspaper publishers are facing: "The real problem, Mr. Newspaperman, isn't that your content isn't online or isn't online with multimedia. It's your content. Specifically, it's what you report, which stories you publish, and how you publish them to people, who, by the way, have very different individual interests. The problem is the content you're giving them, stupid; not the platform its on."
by Vin Crosbie in Rebuilding Media

Travels In Numerica Deserta

There's a problem in the drug industry that people have recognized for some years, but we're not that much closer to dealing with it than we were then. We keep coming up with these technologies and techniques which seem as if they might be able to help us with some of our nastiest problems - I'm talking about genomics in all its guises, and metabolic profiling, and naturally the various high-throughput screening platforms, and others. But whether these are helping or not (and opinions sure do vary), one thing that they all have in common is that they generate enormous heaps of data.
by Derek Lowe in In the Pipeline

Disrobing the Emperor: The online “user experience” isn't much of one

Now that the Web labor market is saturated and Web design a static profession, it's not surprising that 'user experience' designers and researchers who've spent their careers online are looking for new worlds to conquer. Some are returning to the “old media” as directors and producers. More are now doing offline consulting (service experience design, social policy design, exhibition design, and so on) under the 'user experience' aegis. They argue that the lessons they've learned on the Web can be applied to phenomena in the physical and social worlds. But there are enormous differences...
by Bob Jacobson in Total Experience

Second Life: What are the real numbers?

Clay Shirky, in deconstructing Second Life hype: "Second Life is heading towards two million users. Except it isn’t, really... I suspect Second Life is largely a 'Try Me' virus, where reports of a strange and wonderful new thing draw the masses to log in and try it, but whose ability to retain anything but a fraction of those users is limited. The pattern of a Try Me virus is a rapid spread of first time users, most of whom drop out quickly, with most of the dropouts becoming immune to later use."
by Clay Shirky in Many-to-Many

The democratisation of everything

Over the last few years we've seen old barriers to creativity coming down, one after the other. New technologies and services makes it trivial to publish text, whether by blog or by print-on-demand. Digital photography has democratised a previously expensive hobby. And we're seeing the barriers to movie-making crumble, with affordable high-quality cameras and video hosting provided by YouTube or Google Video and their ilk... Music making has long been easy for anyone to engage in, but technology has made high-quality recording possible without specialised equipment, and the internet has revolutionised distribution, drastically disintermediating the music industry... What's left? Software maybe? Or maybe not."
by Suw Charman in Strange Attractor

RNA Interference: Film at Eleven

Derek Lowe on the news that the Nobel Prize for medicine has gone to Craig Mello and Andrew Fire for their breakthrough work: "RNA interference is probably going to have a long climb before it starts curing many diseases, because many of those problems are even tougher than usual in its case. That doesn't take away from the discovery, though, any more than the complications of off-target effects take away from it when you talk about RNAi's research uses in cell culture. The fact that RNA interference is trickier than it first looked, in vivo or in vitro, is only to be expected. What breakthrough isn't?"
by Derek Lowe in In the Pipeline

PVP and the Honorable Enemy

Andrew Phelps: "Recently my WoW guild has been having a bit of a debate on the merits of Player-vs.-Player (PvP) within Azeroth. My personal opinion on this is that PvP has its merits, and can be incredible fun, but the system within WoW is horridly, horribly broken. It takes into account the concept of the battle, but battle without consequence, without emotive context, and most importantly, without honor..."

From later in the piece: "When I talk about this with people (thus far anyway) I typically get one of two responses, either 'yeah, right on!' or 'hey, it’s war, and war isn’t honorable – grow the hell up'. There is a lot to be said for that argument – but the problem is that war in the real historical world has very different constraints that are utterly absent from fantasized worlds..."
by Andrew Phelps in Got Game

Rats Rule, Right?

Derek Lowe: "So, you're developing a drug candidate. You've settled on what looks like a good compound - it has the activity you want in your mouse model of the disease, it's not too hard to make, and it's not toxic. Everything looks fine. Except. . .one slight problem. Although the compound has good blood levels in the mouse and in the dog, in rats it's terrible. For some reason, it just doesn't get up there. Probably some foul metabolic pathway peculiar to rats (whose innards are adapted, after all, for dealing with every kind of garbage that comes along). So, is this a problem?.."
by Derek Lowe in In the Pipeline

Really BAD customer experience at Albertsons Market

Bob Jacobson, on shopping at his local Albertsons supermarket where he had "one of the worst customer experiences" of his life: "Say what you will about the Safeway chain or the Birkenstock billionaires who charge through the roof for Whole Foods' organic fare, they know how to create shopping environments that create a more pleasurable experience, at its best (as at Whole Foods) quite enjoyable. Even the warehouses like Costco and its smaller counterpart, Smart & Final, do just fine: they have no pretentions, but neither do they dump virtual garbage on the consumer merely to create another trivial revenue stream, all for the sake of promotions in the marketing department..."
by Strange Attractor in Total Experience

The Guardian's "Comment is Free"

Kevin Anderson: "First off, I want to say that I really admire the ambition of the Guardian Unlimited’s Comment is Free. It is one of the boldest statements made by any media company that participation needs to be central to a radical revamp of traditional content strategies... It is, therfore, not hugely surprising to find that Comment is Free is having a few teething troubles..."
by Kevin Anderson in strange

The Loom

Category Index
Blink ›
Six-Legged History
More from Brown on Hobbits
Be heard!
Monkey Business
The Loom: The Podcast Edition
Scrape off Those Stickers!
More To Read: Tangled Bank
Dinosaur-eating Mammals (You heard me right)
Bones on the Loose
Hobbit Update

Brains
Crayfish Psychoanalysis
You're a Dim Bulb (And I mean that in the best possible way)
Where Is Your I?
Attention Nutmeggers
An iPod in Your Head
Return of Mad Cow Memories
Brain Revolutions, Old and New
Cheating on the Brain
Zap
Consciousness and the Culture Wars, Part Three
Best of 2004
The Long Road from Genes to God
Babies with Grown-up Brains
The Unwritten Self
Machiavellian Monkeys
The Inescapable Allure of the Reptile Brain
From Souls to Genes
All in the Australian Mind
The Wi-Fi Within
Right and Wrong and Radio
Oh To Be In England
Getting Closer to the Brain Implant
Soul of the South
The Reviews
Fire Up The Tivo
Bioethics of--and in--the Brain
Building and Breaking The Mental Juke-Box
17th Century Soul, 21st Century Mind
West Coast Soul, or How to Get on TV
Flesh Air
Midtown and Downtown
Today's Lunch Special
Of Radio Shows and Pirate Neurologists
Building the World from the Brain Out
Brains, Past and Future
William Safire's 2004 Predictions
Mad Cow Memories
A Little Soul For The Holidays
The Genes Behind Big Brains
Reading the Body
Free Will Starts...Now
Pinker's Choice
This is your brain on racism. Or is that liberal guilt?
Suffering and Knowing
Gross to you, gross to me
Consciousness and the culture wars, part 2
From Genes to Words
Soul Made Flesh: A Preview
10% Myth, 1% Fact?
Heartache is brainache
A Picture of Not Thinking
Consciousness and the Culture Wars
The Reverse Broca

Evolution
Adapting to Life in Yogurt
Talking at Woods Hole
Invisible Gladiators in the Petri Dish Coliseum
Manimals, Sticklebacks, and Finches
Jakob the Hobbit?
Grandma Manimal
The Neanderthal Genome Project Begins
In the Beginning Were the Viruses
Talking Tiktaalik
Worst Science Article Headline Ever?
Wanted: Hominids for Clinical Drug Trials
Speak, Starling
Snakes, Universes, and the Rest
Brains and Bones and Radios
The Final Adventures of the Blind Locksmith
The Blind Locksmith Continued: The Mushy Definition of Complexity
The Blind Locksmith
Leech quest
Walking Towards Land
Learning To Ignore Your Viruses
Pharyngula on penguins
Hipster Dodos
Evolution Resumes in November!
Frivolous Creationist Lawsuits
Mothers, Children, and Genes in Conflict
The Sixty-Million-Year Virus
A Retraction and a Deletion
Where There's Liquid Water...
Wrist Walkers Revisited
This Week in Human Evolution
Tree of Life, c. 2006
Set Your Watch
The Dawn of Brains and Bones
Painting Evolution
The Origin of Species, Side By Side
The Evolution of 3-D
Randy "Flock of Dodos" Olson Speaks
Movie Night
Kid, Someday Your Name Will Be in Lights
A Flock of Dodos, trailed by a journalist
Irish elk of the Jurassic
Hey Wonkette!
Plagiarizing Dinosaurs
Darwiniana
A Complicated Death
They Just Keep Piling On
Updated Cat Evolution
And Introducing Our Latest Creationism-Friendly Politician, The Governor of Texas!
Cat-Blogging from Deep Time
In Praise of Flukes
Michigan Talk
More Fun With Our Post-Modern Politicians
The Other Panda's Thumb
Semiotics of a Leaf--The Dope
The Big Fact-Check: Thoughts On the Day After Dover
Dover: ID is out!
Conservative leader: Intelligent Design is "bull----"
Chimpanzees at Pre-School
Tree or Trellis
Quote Mining, Near and Far
Updating Human Evolution
An Audubon for the Miocene
The Mosquito and the Bottle
Which Came First, the Snake or the Venom?
Book News, Part One
Chronicle of a Death Foretold
The Long, Long Sleep
Beware of Crickets Bearing Gifts
Stay Right There, Mendel
The Semiotics of a Leaf
Hobbit As Monkey?
A Rough Grunt Dictionary
Attention Nutmeggers Again
Now That's A Petition
What's A Gene For?
Of zoos and polls
Hobbits again
A 70-Million-Year March of the Penguins
Florida, Where The Living Is Contradictory
Evolution's Emily Litella?
A Prize Bug
Swarthmore Evolving
The Steps of the Puzzle
A Trip to the Museum
Traditional Norms, Animal-style
Text Versus Subtext
Monday Morning Buffet
Clint Is Dead, Long Live Clint
The Chromosome Shuffle
The Beauty of Deceit
Deepak Chopra Explains It All For You: Conscious Photons!
Bush, Frist...McCain
The Kanisza Virus
A View From the Left (Sigh)
Malaria For Brains
The Tubercular Hominid
The Big Picture
Ghosts in the E. coli machine
Meet Your Inner Mole Rat
A Dog and the Mind of Newton
And Now A Word From the Astronomers...
55,000 Science Teachers: "Stunned and Disappointed" by the President
43,000 Scientists: Bush Puts Schoolchildren At Risk
A Question For The President
Singing Wings, Or Natural Selection's Lesser Known Sibling
Tangling the Tree
It Never Hurts to Ask
Mice, Monkeys, and Muttering
Lucky Octopi
Evidence and exasperation
Light from Dark
Surprises in Jelly
O is for...
An Inordinate Fondness for Beetle Horns
Of Stem Cells and Neanderthals: Closing the Circle
The Mutiny Down Below
Woodpecker Punditry--Predicted and Delivered!
Reports of My Extinction Are Greatly Exaggerated
Humanity's Map
"Blinding New Evidence!"
Flesh on the Bone
Doctor Venom
Love Darts in the Backyard
Dinosaurs Hit the Airwaves
Move Over, Mendel (But Don't Move Too Far)
Who Gets On the Shelf?
Tree Climbing
Evolution at Work (and creationism nowhere in sight)
Growing Up With Dinosaurs
Darwin in the Crib
Conscientious Chimps and Bold Birds
Building Gab: Part Two
Building Gab: Part One
Eyes, Part Two: Fleas, Fish, and the Careful Art of Deconstruction
Eyes, Part One: Opening Up the Russian Doll
This Week's Table of Contents: Eyes and Language
Metaphor, Me-ta-phor!
Gulp
Farewell, Ernst
Mutants Today and In Days Gone By
The Incredible Shrinking Fish and Other Wonders of the Modern World
Of Stem Cells and Neanderthals
The Hobbit War: An Indonesian View
Mysteries Near and Far
Aliens Invade East Lansing
From Enemies to Friends
The Whale and the Antibody
All the News That's Too Big To Print
When It Pays To Be Dumb
Idealogy Versus Isotopes
Hominid Sculpture
Bones on the Loose
Resurrecting Genomes
Getting Sexier All The Time
Canada Evolving
Hobbit Limbo?
Old Apes and Bad Links
Can Two-Thirds of Americans Possibly Be Wrong?
An Award (And An Apology)
What is Old is New
Island of the Lost Hominids
The God Gene Meme
In The Papers
Genetic Ghosts of Hominids Past
The Missing Foe
The Ancestor's Tale Reviewed
Further Adventures in Geological Cowardice
Ignorance For Sale, Thanks To Your Tax Dollars
More on Common Ancestors
Biting the Dust
If These Lice Could Talk
Nobel and Darwin
A Puzzle for the Autumnal Equinox
Deep Time In a Bird's Beak
Getting Closer To Life's Dawn
Channel Surfing For The Inner Chimp
Takes One to Know One
Deadly, Tiny, and Ready For Its Close-up, Mr. DeMille
Spite in a Petri Dish
Adam and His Eves
Evolution meets IVF
Dawn of the Leafy Age
The Little Ones
Taking the Plunge
Love Is A Virus
Mister Adaptation
New Life For Old
Very Noisy Evolution
In the Beginning Was the Borehole
The Game is Over
The Panda's Thumb
Chew On This
The Dog That Didn't Bark In the Night
Angels and Extinctions
Literature Check
The Accidental Tumor
The Wisdom of the Mailbox
Ohio Loses Its Way
Secrets of the Teeth
The Dawn of Medicine, Plus or Minus a Couple Million Years
The Creativity of Microbes
Networks Under Construction
Return of the Howlers
My Darwinian Daughters
Flower Power
Aristotle, Darwin, Watson, and Co. Now Online
The Monkeys Win
Where Have I Heard "Sound Science" Before...?
No SARS in Georgia
Beyond the Cycle
Advances in Deception
You Know What They Say About Male Beetles With Long Horns...
The Howler Test
Orchid Hacks
Never Mind That Boiling Kettle...
Why The Cousins Are Gone
Your Loss is Your Gain
Hamilton's Fall
A (Re) Introduction, Complete With Rams, Plagues, and Chimps
Eight Little Piggies Redux
The Junk DNA Preservation Society
The History of An Orange Glow
Bad Memes in Oslo
Microbe or Mineral?
Recoil from Dollo's Law
Giving skepticism a bad name
More fun with Gregg
Junkburst
Smart Wings of the Jurassic
Multi-Dimensional Mangling
Stalking the Perfect Tree
One gene, many fish
The New Pangaea
Dreams of a Eugenicist Planet?
A New Species of Genius
Fear of a Eugenicist Planet
You Call That Fair?

General
Host Shifting
Synthetic Biology--You are There
Back to Blogging
Not Dead, Just Deadlines
Taking the Temperature on Global Warming Books
Lemonick Blogs
DailyKos Interview
What to do after you lose your job at NASA
Crocodiles and Sentence Diagrams
Comment Jam
Science Blog Convergence
Let Me Draw Your Attention...
On the Virtual Radio Tomorrow
Stumbling On Through the Blogosphere
Half a Mil
Blog Notes
My blog, your microphone
The Book Stack
Okay, It's Not A Nobel, But It's Still Nice
The Bumpy Road to an Upgrade
Blogs: Another Sign of Semi-Respectability
Updates
What the Loom Giveth, the Google Ads Taketh Away
Life Versus Squiggles
Non-Random Sponsor
Like the Elections, Except in Outer Space
Taking Crichton Down a Peg
Climate: A Promising Blog
Technology for Nature
The Morula Solution?
Intelligent Redesign
Hacking Life
A Blog-Free Week
Blog Revived
Mooney on the Science War
No Press Releases, Please
Ugly Comments, Quiet Blogger
Back
Light Blogging
The Loom In the News
Unsound unscience
A Notice to Subscribers
Month One/Staying in Touch
Talking Soul In DC
Big Science and Big Science Books
Venter's Virus--Assembly Instructions Now On-Line
Venter's virus
The Hypothetical Fungus
Reading on the Radar
Blog birth

Hobbits (Homo floresiensis)
Small Girls with Sharp Rocks
Jakob the Hobbit?
Kate Wong on the Hobbit Trail
Do Not Arm-Wrestle With Hobbits
Hobbit As Monkey?
Whose Brain Is It Anyway? (The Further Hobbit Adventures)
Hobbits again
Look! Up in the Sky! Flying Hobbits!
Return to Hobbit Limbo
Hobbits Alive?
Trouble in Middle Earth?
The Hobbit's Brain
Return of the Prodigal Bones
The Hobbit War: An Indonesian View
Hominid Sculpture
Bones on the Loose
Hobbit Update
Hobbit Limbo?
Island of the Lost Hominids

Our Dear Leaders Speak
They Just Keep Piling On
And Introducing Our Latest Creationism-Friendly Politician, The Governor of Texas!
More Fun With Our Post-Modern Politicians
Florida, Where The Living Is Contradictory
Bush, Frist...McCain
And Now A Word From the Astronomers...
55,000 Science Teachers: "Stunned and Disappointed" by the President
43,000 Scientists: Bush Puts Schoolchildren At Risk
A Question For The President

The Parasite Files
Unauthorized Wiretaps in the Garden
The Great Escape
Gross, and then really gross
Caution: Contains Viewing Material That May Not Be Suitable for Younger Cockroaches
Cockroach Zombies Go Cable
Answers to your parasite questions
The Wisdom of Parasites
The Return of the Puppet Masters
A Prize Bug
Sickness All Around
Battle of the Hole Punchers
The Loom's Celebrity Edition
Rime of the Ancient Parasite
Divine Worms