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    Brain Waves

    Entries by Tom Ray
    September 29, 2003

    A Chemistry of MindEmail This EntryPrint This Article

    by Tom Ray The goal of mapping "receptor space" is to chart the relationships between complex alterations in chemical signaling, and resulting changes in mental states. These data are expected to provide an empirical basis for the development of an...

    Continue reading "A Chemistry of Mind"...

    Permalink | Comments (0) | Category: Neuropharma
    September 26, 2003

    A Dynamic Neurochemical SystemEmail This EntryPrint This Article

    by Tom Ray Let's consider a brain-centered reference frame, in which the origin is based on some arbitrary absolute levels of activity at each receptor population. The origin could be the time-averaged activity at each receptor, or no activity at...

    Continue reading "A Dynamic Neurochemical System"...

    Permalink | Comments (0) | Category: Neuropharma
    September 25, 2003

    Mapping Receptor SpaceEmail This EntryPrint This Article

    by Tom Ray I would like to share a metaphor, or image, that I use when thinking about the new pharmacology: receptor space. Imagine a coordinate system based on receptors, one axis for each receptor ("receptor space"). This notion of...

    Continue reading "Mapping Receptor Space"...

    Permalink | Comments (0) | Category: Neuropharma
    September 24, 2003

    Post-Genome PharmacologyEmail This EntryPrint This Article

    by Tom Ray The completion of the human genome has revealed the tremendous complexity of the chemical signaling pathways in our bodies. There appear to be over three hundred different kinds of receptors expressed in the brain. To understand how...

    Continue reading "Post-Genome Pharmacology"...

    Permalink | Comments (0) | Category: Neuropharma
    September 23, 2003

    The Pharmacological Approach to Brain MappingEmail This EntryPrint This Article

    by Tom Ray Why are there so many different neurotransmitter receptors in the brain? What is the functional role of each, and how are they organized in the brain? How are the activities of these transmitter systems and their interactions...

    Continue reading "The Pharmacological Approach to Brain Mapping"...

    Permalink | Comments (2) | Category: Neuropharma
    September 22, 2003

    The Chemical Architecture of the MindEmail This EntryPrint This Article

    by Tom Ray Understanding the chemistry of the brain and the mind that emerges from it is one of the remaining great frontiers of science. Developing a fundamental understanding of the chemistry of the mind will provide us with a...

    Continue reading "The Chemical Architecture of the Mind"...

    Permalink | Comments (8) | Category: Neuropharma